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Turnkey Pharma Systems

Turnkey Pharma Systems

В области фармацевтической промышленности наша фирма предлагает промышленное и лабораторное оборудование, отвечающее высоким современным Американским (USP) и Европейским (CE) стандартам. We are the exclusive representative in Russia and the CIS of a number of large Indian manufacturers of pharmaceutical equipment, raw materials, and hard gelatine capsules, which are jointly produced with Western companies and supply their equipment to Europe and America. We want to emphasize that the equipment manufactured in India provides the most optimal ratio of price and quality. It is produced using the latest technologies, most of the technological developments are carried out jointly with German and Italian companies.

We offer turnkey pharmaceutical companies – lines covering the entire production cycle: from the manufacture of a medicinal product to its packaging in blisters, with further packaging in boxes, namely:

  • ready-made line of equipment for the manufacture of tablets / capsules;
  • equipment for filling capsules with drugs or dietary supplements in solid and liquid form;
  • equipment for packing tablets and capsules in blisters and cardboard boxes, as well as in plastic bottles;
  • production lines for washing and filling ampoules and vials;
  • equipment for sterile filling in plastic ampoules and vials;
  • packaging materials: PVC film, foil and hard empty gelatin capsules;
  • substances for medicines.
Blow/Fill Seal system, model- KNBFS-15/20

Blow/Fill Seal system, model- KNBFS-15/20

New advanced aseptic manufacturing technologies are available for filling liquid pharmaceuticals, including biologics.

In blow-fill-seal (BFS) technology, which is a form of advanced aseptic manufacturing, the container is formed, filled, and sealed in one continuous, automated system. A primary advantage of this technology is reducing human intervention, which reduces the risk of microbial contamination and foreign particulates. BFS has long been used in liquid pharmaceutical applications, including small containers, such as ophthalmic and respiratory drug ampoules, as well as larger volume containers, such as saline or dextrose solutions. More recently, BFS technology has been expanding into injectables and into biologics, including vaccines and monoclonal antibodies (mAbs).

(For ampoules with one set of molds for 10ml ampoule having 15 twin molds of 20 cavities.)
The System is having sequential combination of plastic extrusion followed by blowing, filling and sealing in a rotary mold mechanism. Plastic granules are fed in to the barrel through hopper and a capsule shape parison is extruded. Extruded parison is then taken out of the rotating blow molds and blown in to the shapes of pre shaped cavities of each mold. While the parison is blown in to cavities, filling is being done through stationary nozzles centered between the set of molds. Filled cavities of each mold are being sealed immediately by following set of molds.


High Shear Mixer Granulator

High Shear Mixer Granulator

A high-shear granulator consists of a cylindrical or conical mixing bowl, a three bladed impeller, a chopper, an auxiliary chopper, a motor to drive the blades and a discharge pot. By either circulating hot or cool liquid or steam through the jacket, the mixing bowl is jacketed for heating or cooling the contents of the bowl as the case may be.

The high-shear wet granulation process using high-shear granulator can be divided into 5 stages and they included;

  1. Powder mixing
  2. Binder addition or addition of granulating liquid.
  3. Wetting of powder and nucleation
  4. Growth of granules and densification of the powder.
  5. Granule attrition and breakage.

high shear mixer granulator is an enclosed container with a range of blending equipment that process the powder either from below, above or sideways. The end result/output of this process is a round and compact granule.

Auto Coating Machine

Auto Coating Machine

Auto coater machine is widely applicable for the purpose of coating pallets, granules and tablets. Auto coaters are manufactured with the highest standard of GMP regulation using S.S.316, having user-friendly software and operated through PLC to maintain uniformity of coating and Elimination of manual reference and coater’s expertization. The main application is Film coating with organic solvent / Film coating with aqueous coating and Sugar coating. Auto coater machine is In – built with Auto spray stop in case of disturbance in pan drive to protect tablets or granules from any damage due to system failure. The Pan cabinet is absolutely air tight and ensures no pollution in production environment. Auto coater machine has excellent mixing and tumbling operation by special design of baffles to prevent chipping of tablets. Auto coater machines are available in capacities of 10 to 12 Kgs.

Fluidized Bed Dryer

Fluidized Bed Dryer

Fluidized bed dryer (also called fluid bed dryer) is a kind of equipment used extensively in the pharmaceutical industries to reduce the moisture content of pharmaceutical powder and granules. The equipment works on a principle of fluidization of the feed materials. In fluidization process, hot air is introduced at high pressure through a perforated bed of moist solid particulate. The wet solids are lifted from the bottom and suspended in a stream of air (fluidized state). Heat transfer is accomplished by direct contact between the wet solid and hot gases. The vaporised liquid is carried away by the drying gasses. Sometimes to save energy, the exit gas is partially recycled.

A typical fluidized bed dryer consists of the following components

  • Air preparatory unit.
  • Product container.
  • Exhaust filter.
  • Exhaust blower.
  • Control panel.
  • Air distribution plate.
  • Spray nozzle.
  • Solution deliver.
Mass Mixture Machine

Mass Mixture Machine

Stainless Steel Mass Mixer is Specially designed equipment for product uniformly mixing of dry and wet materials and Mass mixer especially industry demanded for Granules , powder of Ayurveda , Pharma, Food, Herbals, Agro Chemicals & pain powder and Chemicals..

The mass mixer consists of a rigid fabricated structure motor, gear box, mixing drum, stirrer and tilting device. Specially designed self adjusting sealing arrangement of unique design is provided to ensure that no black particle enters into the mixing drum. The material under mixing process can be monitoring through acrylic dust cover and its controls dusting and contaminations. The tilting device is provided to make easy the unloading of the material and easy cleaning of the mixing drum.

MODEL PMM – 50 PMM – 100 PMM – 150 PMM – 200 PMM – 300 PMM – 500
Capacity in Kg 50 100 150 200 300 500
Brim Volume in Liter. 100 200 300 400 600 1000
Working Volume in Liter. 80 160 240 320 580 800
Stirrer RPM 30 30 30 30 30 30
Electric Motor hp / kw 3 / 2.25 5 / 3.75 7.5 / 5.6 7.5 / 5.6 10 / 7.5 15/11.25

salient Features :

  • Design is cGMP – Current Good Manufacturing Practices compliance
  • All Product contact parts AISI 316 & non contact parts AISI 304.
  • Uniform Mixing with paddle blade stirrer.
  • Self adjusting sealing arrangement to avoid entire black particles.
  • Tilting device for easy unloading and cleaning.
  • The interlocked acrylic covers of product container, enclosed drive & Overloads relay protection.

Optional Features :

  • Flame proof electric.

Safety Features :

  • Total drive transmission system enclosed
  • Limit switch installed in the top lid ensure lid is closed
  • Overload relay Protection.